Highlights
Feline Coronaviruses: Research, Pathogenesis and Therapeutics is a premier, peer-reviewed international journal dedicated to advancing the scientific understanding of feline coronaviruses (FCoV) and their associated clinical outcomes. The journal serves as a comprehensive platform for interdisciplinary research, bridging fundamental virology with translational clinical applications. Our mission is to catalyze progress in the prevention, diagnosis, and treatment of FCoV-related diseases through the dissemination of high-quality original research, critical reviews, and cutting-edge technological innovations.
Our scope rigorously covers, but is not limited to, the following core areas:
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Molecular Virology & Viral Evolution: Genetic characterization, phylogenetic analysis, and the molecular mechanisms underlying the biotype switch from avirulent FCoV to virulent FIPV (Feline Infectious Peritonitis Virus).
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Epidemiology & Host Dynamics: Transmission patterns, risk factors, and the prevalence of FCoV in diverse feline populations, including domestic cats, breeding catteries, and wild felids.
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Host-Pathogen Interactions & Immunology: Innate and adaptive immune responses to FCoV infection, immune evasion strategies, cytokine storm syndromes, and the immunopathogenesis of FIP.
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Advanced Diagnostics: Development and validation of sensitive and specific molecular assays (RT-qPCR, sequencing), serological biomarkers, and point-of-care testing for early and accurate FCoV detection.
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Antiviral Therapeutics: Preclinical and clinical evaluations of novel antiviral agents, including nucleoside analogs (e.g., GS-441524, remdesivir, molnupiravir), immunomodulatory drugs, and combination therapy regimens.
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Vaccine Research & Prophylaxis: Design and testing of next-generation vaccines, including mRNA, viral-vector, and subunit vaccine platforms aimed at preventing FCoV infection or FIP development.
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Pathology & Clinical Management: Histopathological characterization of FCoV-associated lesions, clinical case management protocols, and long-term outcomes of treated patients.
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Public Health & One Health Perspectives: Surveillance of FCoV as a model for coronavirus biology, comparative coronavirology, and the implications of antiviral resistance.
By fostering collaboration among virologists, immunologists, veterinarians, pharmacologists, and molecular biologists, Feline Coronaviruses: Research, Pathogenesis and Therapeutics aspires to be the definitive global reference for the scientific community, ultimately translating bench-side discoveries into tangible benefits for feline health and welfare.
